Showing posts with label Cause. Show all posts

Can Eating Fish Cause Prostate Cancer?

Tuesday, December 20, 2011 · Posted in , , ,

It seems that there are a lot of different risk factors for getting prostate cancer. Among some of the most popular are: genetic predisposition, being of African descent, eating red meat, smoking, drinking too much alcohol, eating dairy products and having too many different sex partners. (If you are a Black male with a lot of sex partners I'd cut back on my dairy.)

Just when it seems like there's not much left that's tasty or fun, the American Journal of Epidemiology has added one more to the list. Men who eat fish are 2.5 times more likely to develop aggressive prostate cancer. Admittedly, giving up fish isn't as tough as most of the other things on the above list, but we always thought fish was good for us. Isn't it supposed to be brain food or something?

Researchers from Seattle's Fred Hutchinson Cancer Research Center did a prostate cancer study on 19,000 men age 55 and up. After a few years they tested a subset of 3,000 of them and discovered that the men who had developed an aggressive form of prostate cancer also had the highest levels of DHA (an omega 3 fatty acid). This was shocking to them in that they expected a higher level of omega 3 might even protect against cancer. If it didn't prevent cancer they certainly didn't expect it to cause cancer. The men with the highest levels of DHA had a much higher incidence of this disease. Not only did they have prostate cancer but an aggressive form of it. The kind that kills you quickly. It was also interesting to note that very few of the subjects took omega 3 supplements. Most of them got it from eating fish.

If you Google "Omega 3 prostate cancer fish" it's all over the web. Eating fish increases your risk of getting an aggressive form of prostate cancer by a significant amount. The results are in. The good news is that fish still make excellent fertilizer in your garden.

This is a good time to make a disclaimer. I'm not a doctor. It's been so long since I've gotten my degree in Biology that I'm probably not even a good scientist. I'm a Caveman. However, something here seemed fishy to me. I do know that cavemen ate fish. To suddenly find out that fish are bad for us just seems counter-intuitive, so I did a little digging.

This study didn't start out to be about omega 3 at all. The omega 3 findings were anecdotal. It was an experiment sponsored by a major drug company that sells finasteride. Finasteride is a drug that is synthesized from progestrone (a female hormone) that shrinks enlarged prostates and promotes hair growth on aging balding men. The drug company sponsored this study in the hopes that their drug might also prevent prostate cancer. How cool would that be? A pill so that you don't have to get up at night to pee, prevents prostate cancer and even grows your hair back.

All 19,000 men at the beginning of this study and all 3,000 that were eventually tested for prostate cancer had been taking finasteride. As a Caveman, here is what I would draw as a conclusion from this study: Most of them could sleep through the night without getting up to urinate, most were hairier, a few that ate fish developed aggressive prostate cancer.

I think the only logical conclusion one can draw from this study is that it isn't a good idea for men to eat both fish and finasterides.

So, can eating fish give you aggressive prostate cancer? Maybe. Maybe not. Because it's so hard to check for caveman prostate cancer in the fossil records, we need to do more research.

Kittredge Kymla has a BS in Biology, Chemistry and Physics from Wayne State University. He writes about the Paleo diet and caveperson lifestyle. For a collection of recipes and caveman lifestyle articles, all glued together with a little humor, please visit http://cavemanhomecompanion.com/.


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Scientists Zero in on Prostate Cancer Cause

Wednesday, November 23, 2011 · Posted in , , ,

The prostate is a gland in the male reproductive system. Prostate cancer occurs when cells in the prostate mutate and begin to multiply out of control. The peripheral zone of the prostate usually develops cancer first. These small clumps of cancer cells attach to an otherwise healthy prostate. When and if the cells begin to multiply, they can spread to the surrounding prostate tissue. Eventually a tumor may invade nearby organs, such as the seminal vesicles, bladder or rectum. Or tumor cells may travel into the lymphatic system and the bloodstream. Often those with prostate cancer have no symptoms. Others experience similar symptoms to those found with BPH, including trouble with sexual function.

When looking for a cure for prostate cancer, scientists have focused on "androgen receptors." Androgens are hormones (such as testosterone) that are important for normal male sexual development before birth and during puberty. Androgen receptors allow the body to respond appropriately to these hormones. Typical cancer treatments involve drugs that slow production of androgen. But, according to researchers, this type of treatment generally becomes less effective over time, as cancer cell resistance strengthens and multiplies.

It's exciting news then, to read about some cutting-edge research being done at the Michigan Center for Translational Pathology. There, scientists believe they have uncovered the primary cause of prostate cancer - and it has very little to do with androgen receptors. The main cause of cancer could, in fact, be the fusion of two genes. When these two genes fuse, it sets the stage for abnormal prostate cell growth.

The research team likens gene fusion to an on switch for prostate cancer development. The cancer is set in motion with the initial fusion of a prostate gene with a cancer-causing gene. The researchers were able to use high-tech genetic mapping techniques to discover that, once fusion takes place, androgen receptors get blocked, in turn cutting off normal prostate cell growth while allowing cancer to spread.

The research team concludes that their study shows the underlying problem in prostate cancer is the presence of gene fusion, not the androgen receptor. In some contexts, androgen signaling is actually a good thing, but the presence of the gene fusion blocks androgen receptor signaling. This in turn alters normal prostate cell development.

It will be interesting to see if scientists can use this discovery to press forward and find a cure for prostate cancer. Perhaps there will be a way to stop gene fusion from happening, thereby protecting healthy prostate genes from cancer-causing genes. And if this could be figured out for cancer, perhaps it might provide clues about how to prevent other types of cancer as well.


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Erectile Dysfunction Treatments - Understanding The Cause So You Can Correctly Treat Your ED

Wednesday, July 21, 2010 · Posted in , , , , , ,

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What are the best forms of erectile dysfunction treatments? There are actually several different types available. Which one you use will depend on what is causing your ED. Once you determine the cause, you can more easily treat the problem.

The majority of cases are caused by psychological issues. Stress, anxiety, and relationship issues all contribute to your inability to get an erection. Your doctor will want to roll this out before pursuing other treatment measures. One way to check is to try to masturbate. If you are not able to get or maintain an erection during that, you may have another deeper cause.

Treatment for psychological issues is usually counseling. You can also try herbal measures to increase mood and desire.

Lifestyle issues are another common cause. Over eating, drinking, and smoking all inhibit your blood flow. If not enough blood gets to your penis, you cannot get and maintain an erection. To fix this, you will need to diet and exercise. In the meantime, your doctor may prescribe medication to help.

The final cause of ED is medical in nature. Prescription medications and certain diseases both contribute to your inability to get an erection. The most common treatment for this is medication. However, this will not work for every situation. Your doctor may even recommend surgery. However, you should avoid this if at all possible. It can seriously inhibit your ability to enjoy sex later.

The form of erectile dysfunction treatments you choose will depend on what is causing the problem. Once you have that figured out, it's much easier to choose your treatment.

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