Impact on the prognosis of chronic renal failure, following several cases more common: (1) of the original kidney disease and chronic renal failure is closely related to the prognosis. (2) all kinds of infection is the most common effects of chronic renal failure prognostic factors, including respiratory tract and urinary tract infection the most common. (3) urinary tract obstruction is a common factor affecting the prognosis, and urinary tract infections often coexist. (4) renal toxicity of drugs used. (5) various reasons for the lack of renal perfusion, such as severe vomiting, diarrhea caused by shock, low blood pressure, long-term excessive use of diuretics, and so on. (6) various causes of heart failure. (7) renal hypertension on renal function has a direct role in damage. (8), such as water electrolyte imbalance.