Gout is a lifelong disease, it's condition development of the entire process can be divided into the following four: (1) hyperuricemia period: also known as pre-gout, in this period the patient can no clinical symptoms of gout, only for the performance of serum uric acid increased. (2) early gout: This period from hyperuricemia developed from. Prominent symptoms of acute gouty arthritis attack. In acute arthritis disappeared after the attack joints can be fully returned to normal, not left over from the damage, but can be repeated attack. This usually subcutaneous the formation of tophi, there is no obvious kidney disease such as uric acid nephropathy and the formation of kidney stones, kidney function was normal. (3) gout medium-term: this period because of repeated gouty arthritis caused by acute injury to a joint varying degrees of bone destruction and dysfunction, chronic gout. Gout can be a subcutaneous stone, may have uric acid nephropathy and the formation of kidney stones, kidney function may be normal or slightly decreased. (4) advanced gout: a clear joint deformity and dysfunction, the increase in the number of subcutaneous tophi, the size of the increase can Pokui a white crystalline salt urine. Uric acid nephropathy and kidney stones to develop and kidney function decreased significantly, there azotemia and uremia.
