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Proton therapy is external beam radiotherapy in which protons are directed at a tumor. The radiation dose that is given through protons is very precise, and limits the exposure of normal tissues. This allows the radiation dose delivered to the tumor to be increased beyond conventional radiation doses. The result is a better chance for curing cancer with fewer harmful side effects.

Unlike X-rays, protons can be manipulated to release most of their energy only when they reach their target. With more energy reaching the cancerous cells, more damage is administered by each burst of radiation while sensitive, healthy lung tissue is better protected from the effects of radiation.

Ramesh Rengan, MD, PhD, assistant professor of radiation oncology at Penn Medicine, evaluates the potential of proton therapy for lung cancer in this physician interview.

Listen to Dr. Rengan talk about the potential of treating lung cancer with proton therapy at Penn.