Gout is an ancient disease, in the past several thousand years of Egyptian mummies have been found on the signs of gout. In 2070 more than 400 years, people have a sense of gout. The first description of the characteristics of this disease gout in ancient Greece, Hippocrates, his main gouty arthritis of the characteristics of a well documented. Gout in the past because of the incidence less, and many people do not understand the disease, gout that is incurred by the cold and joint pain, in fact otherwise. So, what is Gout causes? In the human body has a substance called purine, mainly in the form of purine nucleotides, as energy supply, regulating metabolism and composition, such as coenzyme plays a very important role. When its metabolism disorder and will be cause gout. After a series of purine metabolism changes, the final product is the formation of uric acid. Uric acid in the human body there is no physiological function, in normal circumstances, in the uric acid, 2 / 3, from the kidney, and the remaining 1 / 3 discharged from the gut. Uric acid is constantly in formation and excretion, and it in the blood to maintain certain concentration. Normal contained in a litre of blood uric acid, male mole below 0.42 cents, women no more than O. Moore 357 cents. Purine Synthesis and in the decomposition process, the involvement of a variety of enzymes, because of congenital abnormalities or certain factors not yet clear, metabolism disorder, or an increase of uric acid from the reduction results can cause high urine acidosis. When the excessive concentration of uric acid, sodium acid that is in the form of deposits in joints, and soft tissues, cartilage and kidneys, cause foreign body inflammatory response organizations, has become the bane of gout caused.
