Genetic factors: nasopharyngeal carcinoma were seen mainly in the yellow people. South China (Guangdong, Guangxi, Hunan, Fujian), and other provinces and some Southeast Asian countries is the world's highest incidence rate of nasopharyngeal carcinoma region. Guangdong Province again Guangzhou, Foshan, Zhaoqing and other areas of the highest incidence rates per 100,000 males in the 18 to 27 individuals have breast cancer, while women accounted for 8 to 9. Even if the high incidence area who moved to distant, as to the northeast, their descendants are still maintaining a very high incidence tendency This shows that the occurrence of nasopharyngeal carcinoma has obvious racial sensitivity. In addition, both in the high incidence area or in low-incidence areas, can be found familial aggregation of the tendency. For example, the census found in this typical example, a three generations of 49 people, 10 people suffering from cancer, of which 9 were nasopharyngeal carcinoma. It can be said that genetic factors in the etiology of the NPC plays an important role.
Virus: 1964, it was Africa's children from the successful cultivation of malignant lymphoma cells in a tumor, under electron microscopy, and found a large number of herpes virus particles, and was named EB virus, but studies have shown that this virus and nasopharyngeal closely related to cancer. For example, the serum of patients with nasopharyngeal carcinoma is the EB virus antigen specificity of the antibody response, and the amount of antibodies from early to late in the development process of growing; EB virus exists in a large number of nasopharyngeal carcinoma biopsies; EB virus will not only enable human tissues, but also closer to human primates malignant change in the organization, with a clear role to the tumor, and so on. Based on these results, some people might even think that EB virus is the cause of nasopharyngeal carcinoma.
Environmental carcinogens factors: Many studies and experimental results show that the NPC and the high incidence area in the living environment, with food, clothing, shelter and transportation contacts in a number of carcinogenic substances. For example, many high incidence area residents at an early age like to salted fish, salted fish containing more nitrosamine compounds in the patient's household dust contains a lot of the multi-ring aromatic hydrocarbons; In addition, in areas with high air, water, food even in the patient's hair trace elements contain more nickel, and so on, these substances are considered to have a carcinogenic effect. On the NPC and the relationship between environmental carcinogens, there are some different views.
In short, nasopharyngeal carcinoma in secret, people also need to be further explored.
Virus: 1964, it was Africa's children from the successful cultivation of malignant lymphoma cells in a tumor, under electron microscopy, and found a large number of herpes virus particles, and was named EB virus, but studies have shown that this virus and nasopharyngeal closely related to cancer. For example, the serum of patients with nasopharyngeal carcinoma is the EB virus antigen specificity of the antibody response, and the amount of antibodies from early to late in the development process of growing; EB virus exists in a large number of nasopharyngeal carcinoma biopsies; EB virus will not only enable human tissues, but also closer to human primates malignant change in the organization, with a clear role to the tumor, and so on. Based on these results, some people might even think that EB virus is the cause of nasopharyngeal carcinoma.
Environmental carcinogens factors: Many studies and experimental results show that the NPC and the high incidence area in the living environment, with food, clothing, shelter and transportation contacts in a number of carcinogenic substances. For example, many high incidence area residents at an early age like to salted fish, salted fish containing more nitrosamine compounds in the patient's household dust contains a lot of the multi-ring aromatic hydrocarbons; In addition, in areas with high air, water, food even in the patient's hair trace elements contain more nickel, and so on, these substances are considered to have a carcinogenic effect. On the NPC and the relationship between environmental carcinogens, there are some different views.
In short, nasopharyngeal carcinoma in secret, people also need to be further explored.
