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HYPERTENSION DRUGS CAN RAISE BP.....!!

Monday, November 21, 2011 · Posted in ,


A new study suggests that commonly prescribed drugs used to lower blood pressure can actually have the opposite effect-raising blood pressure in a statistically significant percentage of patients.

The study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that doctors could avoid this problem-and select drugs most suitable for their patients-by measuring blood levels of the enzyme renin through a blood test that is becoming more
widely available.

"Our findings suggest that physicians should use renin levels to predict the most appropriate first drug for treating patients with hypertension," says lead author Michael Alderman, professor of epidemiology & population health and of medicine at Einstein.

"This would increase the likelihood of achieving blood pressure control and reduce the need for patients to take additional antihypertensive medications."

The study involved 945 patients who were enrolled in a workplace antihypertensive treatment program in New York City from 1981 to 1998. All had a systolic blood pressure (SBP) of at least 140 mmHg. SBP, the top number in the blood pressure reading, represents the amount of force that blood exerts on the walls of blood vessels when the heart contracts. No patients were receiving treatment for high blood pressure before enrolling in the study.

The patients were given a single antihypertensive medication, either a diuretic or a calcium channel blocker (so-called "V" drugs, which lower blood volume) or a beta blocker or an ACE inhibitor ("R" drugs, which lower levels of renin, an enzyme secreted by the kidneys that plays a key role in maintaining blood pressure).

Plasma renin activity (PRA) and SBP were measured at enrollment, and SBP was measured again after one to three months of treatment. The renin level predicted those patients who were most likely to have a favorable response with either an R or a V drug. In addition, for both R and V drugs, the renin test was able to identify those patients most likely to experience a "pressor response"- a clinically significant increase in SBP of 10 mmHg or more.

Overall, 7.7 percent of the patients exhibited a pressor response. The highest percentage of pressor responses-16 percent-occurred in patients with low renin levels who were given a beta blocker or an ACE inhibitor (R drugs).

Alderman says that two groups of patients might especially benefit from having their renin levels measured: patients being prescribed antihypertensive drugs for the first time and patients who are taking multiple antihypertensive drugs when one or two might work just as well. "With renin testing, you will more often get blood pressure under control with less therapy," he adds.

The study appears in the online edition of the American Journal of Hypertension.
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Health Benefits of Ginseng to Treat Impotence and Depression Naturally: Optimum Dosage and Precautions of Ginseng Supplements

Monday, August 1, 2011 · Posted in , , , , , , , ,

Ginseng is one of the most popular herbs which is added to different types of health drinks, energy tonics, fruit juices and vitamin supplements due to its potential benefits like enhancing energy levels and ability to fight stress. These health drinks are popular among teenagers, but often these drinks contain very little quantity of this wonder herb. Panax Ginseng is also referred to as the Asian Ginseng which has been used in Chinese medicines for over thousands of years for longitivity and to enhance quality of life. This Chinese Ginseng is different than American Ginseng (P.quinquefolius) and Siberian Ginseng (E. Senticosus), which has completely different effects on human health.

Ginseng has a great
influence on the
endocrine system
Ginseng Health Benefits: Prevents Cancer, Boosts Immunity and Treats Impotence 

The medicinal part of the Ginseng herb is its slow growing root which contains thirteen different ginsenosides, which are the active ingredients of the herb. In addition the herb contains panxans, which are substances believed to lower blood sugar levels and polysaccharides, which play a crucial role in boosting the immune response. The major health benefits of Ginseng herb include,
  • A large scale study conducted in Korea found that the use of ginseng reduced the risk of developing cancer by half. Ginseng is considered to boost the production of “killer T cells”, which are the part of the cellular immunity of the body and play a crucial role in cancer prevention. Further, as this herb stimulates the immune system it also plays a protective role against common infections like flu.
  • Ginseng plays a crucial role in regulating the production of stress hormones by support the endocrinal organs namely the pituitary gland and the adrenal glands. This enhances the ability of an individual to combat stress and also is effective in treating fatigue and feeling of tiredness.
  • Ginseng has a direct action on smooth muscle tissue and hence is considered effective in management of erectile dysfunction and impotency in males. Some claims indicate that this herb increases testosterone and sperm production in the body and thereby enhances fertility in men. 
Optimum Dosage of Ginseng Supplement: Precautions while taking Ginseng Supplements
Though the use of the herb is rarely associated with side effects, there are certain factors that need to be taken into consideration while using this herb as a supplement,
  • Though ginseng may be available in a variety of forms including powder, tincture, tablets and capsules, it is always recommended to consume standardized products that contain about 7% ginsenosides. Ginseng powder and tinctures are considered more potent than other forms of the herbal supplement
  • Avoid ginseng when pregnant or when one suffers from uncontrolled hypertension. Ginseng also needs to be avoided in individuals with cardiac arrhythmias
  • Ideal dose of ginseng herb ranges between 100 mg- 250 mg per day. However it can be increased to twice the dosage, especially in individuals recovering from a chronic illness or a major surgery.
    • Ginseng helps control
    depression and impotence
  • Side effects associated with ginseng include headaches, stomach upsets, insomnia and restlessness. In females ginseng is often associated with breast tenderness and irregular menstrual bleeding. 
Ginseng Supplements for Depression: Ginseng controls Blood Sugar Levels and Diabetes
In addition Ginseng Supplements play a crucial role in management of depression and diabetes,
  • In a study conducted on individuals suffering from type 2 diabetes, it was observed that 200 mg of ginseng supplement each day helped lower the blood sugar levels considerably compared to those on placebo
  • In another study it was observed that ginseng can stimulate the production of endorphins, which are ‘feel good’ hormones which play a crucial role in management of depression
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Body Red Alert

Wednesday, April 27, 2011 · Posted in , , , ,

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