We usually refer to the HCC generally refers to a variety of reasons the primary cause of hepatocellular carcinoma in the liver. Hepatitis B virus and liver cancer is most closely associated, Liver cancer patients in 75% of hepatitis B virus surface antigen positive hepatitis B virus is the major cause of primary liver cancer. Application of polymerase chain reaction with hepatocellular carcinoma cancer in the surrounding tissue detection of hepatitis C virus RNA, the hepatitis C virus and liver cancer are related, it is reported that the hepatitis C and hepatitis B infection increased overlap the opportunities to the development of liver cancer. Hepatitis C virus can lead to liver cancer because the incidence of hepatitis C virus is likely to have a direct carcinogenic effect, or have the hepatitis C virus to the occurrence of liver cirrhosis, liver cirrhosis and hepatocellular carcinoma to further development. The real mechanism is currently being examined.