Breast Cancer What are the different types of pathology

Monday, March 31, 2008 · Posted in

Pathological types of breast cancer by means of tumor specimens pathological morphology, thereby determining the degree of development of breast cancer, sources, change of the degree of differentiation, and so on. Many types of breast cancer pathology, and some sources named the organization: as lobular carcinoma, ductal adenocarcinoma; some organizational characteristics of the lesions named: If medullary carcinoma, hardware cancer, cancer alone; named in some lesions: If carcinoma in situ, early cancer, invasive carcinoma, but some cancer cells to the differentiation of naming: If undifferentiated carcinoma, and poorly differentiated carcinoma, differentiated carcinoma, well-differentiated carcinoma.
With histopathological closely integrated with the clinical, pathological types of cancer cells gradually to the surrounding tissues based on the extent of violations and the possibility of distant metastasis size classification. Roughly divided into: Non-invasive cancer, early invasive carcinoma, and invasive carcinoma.
(1) non-invasive cancer: also known as carcinoma in situ, that cancer cells confined to the basement membrane of epithelial growth of tumors did not transfer. Including lobular carcinoma in situ and ductal carcinoma. Accompanied the various breast diseases, and sometimes can be seen next in invasive carcinoma. Carcinoma in situ development has been slow and become invasive several years.
(2) early invasive carcinoma: from the development of invasive carcinoma in situ in the early stages of cancer of the epithelial basement membrane breakthrough, but the extent is still infiltrating shallow, less foci in the transfer. Including early invasive lobular carcinoma in situ and ductal carcinoma in early infiltration.
(3) invasive cervical cancer: cancer of the epithelial basement membrane breakthrough has been restricted, widespread violations of the surrounding tissue, tumor metastasis is high. Based on the original cancer site from the mammary epithelial organizations, or other organizations, is divided into invasive cancer special, special non-invasive cancer.
① special non-invasive cancer: including invasive lobular carcinoma, invasive ductal carcinoma, only cancer, medullary carcinoma, hardware carcinoma, adenocarcinoma.
② special invasive cancer include: papillary carcinoma, medullary carcinoma, adenocarcinoma, adenoid cystic carcinoma, adenocarcinoma sweat, squamous cell carcinoma, nipple Pagets disease.
③ rare cancer include: spindle cell carcinoma, sarcoma cancer, signet ring cell carcinoma, fibroadenoma, such as cancer.
Such classification of clinical prognosis is more practical guidance. Generally believe that: good prognosis carcinoma in situ, followed by the early invasive carcinoma, and invasive carcinoma of the poor prognosis. Special invasive cancer and the prognosis is better than non-special invasive cancer.
In addition, pathological classification of breast cancer by histological features are divided into: epithelial tumors, epithelial tissue and mixed connective tissue tumors. Haagensen also Classification: special-cancer and non-specific cancer.
Pathological type is a highly professional in the diagnosis process. First need to obtain accurate breast tumors large enough samples were fixed, technical professionals to deal with pathology (embedding, slicing, staining, etc.), can be processed under the microscope to watch the pathological biopsy, finally, the need to have extensive experience of Pathology doctor "Film" - a pathological diagnosis. Often encountered in clinical practice in other hospitals some patients were diagnosed as breast cancer, treatment in the hospital needs to be done pathological diagnosis. At this point, we must proceed from the original treatment of hospital pathology borrowed have produced good slice of organizations or wax block, to the pathological diagnosis by doctors, not to make accurate pathologic diagnosis.

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