How early detection of colorectal cancer samples

Saturday, March 29, 2008 · Posted in

Colorectal cancer refers occurred in the rectum and the entire colon (ascending colon, transverse colon, descending colon and sigmoid colon) cancer, Clinical is one of the common malignancy. A large number of information that, due to living conditions and the lifestyle of the big changes in the incidence of colorectal cancer showed an upward trend, especially in large and medium-sized cities, age of onset and more about the 45-year-old. Incidence rates of men and women are basically the same.
The incidence of colorectal cancer accounts for about systemic cancer 12% to 15%. Carcinoid tumors in the rectum, sigmoid colon connect about 60 percent more than other ministries distributed in the colon. The cancer in the rectum and about 80% more, digital rectal examination checks can be found. Clinically, anal examination that the diagnosis of cancer is very important.
Colorectal cancer incidence is generally believed that the reasons for a variety of pathogenic factors synergy results. Some studies show that diet and lifestyle changes and the irrational structure of the incidence of colorectal cancer are closely related. 1, genetic factors, about 20 percent of patients with colorectal cancer in genetic factors may play an important role. 10 per cent of them for multiple familial polyposis; 5% ~ 10% for hereditary nonpolyposis colorectal cancer disease, but have found their molecular genetics foundation and DNA replication errors, and have found relevant mismatch repair genes. 2, benign tumor malignant and benign tumors is the common colorectal polyps, the polyps are mucosal hyperplasia formation of vegetation, sustained spherical. Generally considered adenomatous polyps into cancer takes years. The more broad-cancerous polyps may basement greater, the greater the cancerous polyps higher the rate. 3, enteritis diseases and chronic diseases such as stimulating a broad range of ulcerative colitis, intestinal mucosa repeated destruction and restoration, the course more than 10 years prone to cancer, schistosome eggs, chronic inflammation and Persistent diverticulum anal fistula can be induced cancer . Recent data also show that for many years hemorrhoids carcinogenesis may occur, and the higher cancer rate. 10 did not rule carcinogenesis rate of 5 percent. 4, environmental factors, and 40% to 60% of the environmental factors and to a certain extent, diet, nutrition-related. So diet is considered extremely important factor. ① high-fat, high-protein, low cellulose food can increase the incidence of colorectal cancer. ② fried, food, salted products containing carcinogens, the other a lack of certain trace elements may also increase the incidence of colorectal cancer.
Early colorectal cancer can be no symptoms, with the condition, according to lesions of the site, produce different clinical manifestations. Traits such as changes in bowel habits or will the increase in fecal blood and mucus, fecal of thinning, anal sinkers, pain flu, constipation or diarrhea and abdominal pain, intestinal obstruction symptoms, can occur suffering from weight loss, fatigue, anemia, and other systemic symptoms . Because cancer location and the growth of different types of pathology, the sequencing of symptoms varies. Right colon cancer, most of anemia, abdominal mass, abdominal pain, weakness and other symptoms of systemic clinical manifestations. Few sudden hematochezia for medical treatment, a handful of constipation, it frequently, and other symptoms. Left colon cancer stool blood, mucus, they frequently caused obstruction of common than the right colon cancer may have abdominal pain, symptoms such as abdominal distension, a right colon cancer rare anemia. Early symptoms of rectal cancer is Defecography habits changed and the original laws of the people have become Defecography no laws, and there will be increased frequency or constipation, Pai not flu, it still felt unwell after anus. Subsequent performance for fecal blood, hematochezia and mucus, with the development of disease symptoms appeared rectal stimulation, it intended frequency, then the more anal catch flu. If violations related organizations can produce symptoms. Cancer patients have these symptoms more often "chronic dysentery," "enteritis" and misdiagnosis.
Due to the lack of specificity of colorectal cancer clinical manifestations, and the patients have insufficient understanding, self-awareness of poor health, treatment later. Often "dysentery, colitis, hemorrhoids," to diseases such as drug treatment, but only to be ineffective in the medical or surgical treatment, the doctors of colorectal cancer or not vigilant undergraduate Room common diseases, multiple thinking determining potential impact could easily lead to misdiagnosis. The prognosis of different pathological staging big difference, so when the above symptoms should be promptly to the hospital for medical treatment, so as to avoid delays illness.

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