Chronic kidney disease caused by renal dysfunction is divided into four stages: (1) reduced ability to stage renal reserve: renal unit reduced by 20% to 50%, renal excretion and regulatory function is good, BUN and creatinine are more than the normal range, patients with asymptomatic. (2) stage renal failure: renal unit reduced by 50% to 70%, renal excretion and regulatory function decline in nocturnal enuresis, fatigue, nausea, vomiting, diarrhea and symptoms of anemia and kidney function poor concentration, blood urea Nitrogen and creatinine increased significantly, will have acidosis. (3) stage renal failure: renal unit to reduce 75 percent to 90 percent, nocturnal enuresis, and serious anemia and uremic poisoning symptoms of systemic, low calcium, high-phosphorus, chlorine and high hyponatremia. Metabolic acidosis obvious, but have no hyperkalemia. (4) terminal uremic stage: residual renal unit <10%,>