Heart weight increase, which is about twice the normal. The heart enlargement, myocardial grey and relaxation. Although the heart wall myocardial hypertrophy, but room cavity wall thickness is still room to expand and close to normal. Endocardium can also be thickened. Cavity wall containing many see thrombosis. Common myocardial fibrosis, a focal distributed in the wall of the inner edge, a wall-damaged Kexin, pacing the heart of the conduction system violations may be. The heart of the microscope examination found that the lack of specificity. Fiber can see myocardial hypertrophy, condensation nuclei, deformation or disappeared, a cavity formed within the cytoplasm. More fibrous tissue, or because of increased collagen organization, or focal myocardial fiber was replaced by fibrous tissue. Myocardial fiber cable can be of fiber-like organization by the partition. Endocardial in the collagen and elastic fibers has also increased. Different degrees of degeneration can see that most of myocardial cells dissolved, especially more common in cases of long duration. Electron microscopy see myocardial mitochondrial swelling, broken or disappeared ridge; muscle serous space to expand, fibrous material and the granular lipofuscin; myofibril can disappear. Cardiomyopathy contraction of the heart weakened. Early capacity, such as left ventricular systolic left ventricular pressure increased slow down, slow down the speed of Penxue. At this point stroke volume decreased by compensatory accelerated heart rate, cardiac output can still maintain. After the left ventricle not emptying, the residual blood, end-diastolic pressure increased, the progressive development of left heart failure. Long left atrium, pulmonary artery pressure have increased in the last right heart failure. A small number of cases of disease mainly to the right ventricle, the development of right heart failure. Ventricle of the heart valve ring expansion to expand, resulting in the tricuspid valve or mitral regurgitation. Cavity expansion, increased tension within the heart wall, oxygen consumption increased, myocardial hypertrophy, accelerated heart rate caused relatively myocardial ischemia, and myocardial oxygen perturbation has the ability to limit and thus can cause angina. Cardiomyopathy involves pacing and transmission system can cause all kinds of arrhythmia.
